This content references scientific studies and academic research, and is fact-checked to ensure accuracy.

Our teamof licensed nutritionists and dietitians strives to be objective, unbiased, and honest.

Losing weighttakes a tremendous amount of disciplineespecially if you aim to lose 50 pounds or more.

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While there are a handful of not-so-pleasant changes that go with it, the good outweighs the bad.

And if you need help getting there, check out our tips forhow to lose 50 poundsor more.

Your Taste Buds Change

No, you’re not crazyfooddoestaste different once you’ve lost weight.

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The good news: These changes could help youlose more weight and keep it off.

Looking for more helpful tips?

The result: A more efficient process for storing and re-collecting new information.

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Your Metabolism Slows Down

One of the downsides of a trimmer waistline: Aslower metabolism.

See, bigger things require more energy (read: calories) to function.

In fact, Freter will see post-surgery patients whose daily calorie needs have dropped by a whopping 800 calories.

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Exercise will be key for maintaining your new weight, he adds.

Your Skin Sags

Another drawback to significant 50-pound weight loss?

Loose, saggy skin.

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You lose fat, but all the skin that surrounded the fat may still be there.

According to Freter, many patients with sagging skin turn to plastic surgery for help.

Your Eyes Are Healthier

Weight loss is one way to keep those peepers healthy.

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As researchers note, this may be one reason why obesity can lead to degeneration of the retina.

As you lose 50 pounds of insulation, you may need to shore up your sweater collection.

So, if you lose 50 pounds, that’s the equivalent of 200 pounds of pressure!

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If you have knee osteoarthritis, get ready for some relief.

Department of Health and Human Services.

One possible reason is that fat tissue produces higher amounts of estrogen.

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High estrogen levels increases the likelihood of developing breast, ovarian and other types of cancer.

Another possible link between obesity and cancer is chronic inflammation.

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